Serious asthma events with mometasone furoate plus formoterol compared with mometasone furoate
نویسندگان
چکیده
منابع مشابه
Adrenal suppression with mometasone furoate/formoterol.
journal.publications.chestnet.org The rationale for perioperative bridging is anchored on mitigating the risk of major cardiovascular events, including stent thrombosis, in patients who require surgery and in whom the associated risk of bridging-related bleeding is acceptably low. A number of agents, including unfractionated heparin, low-molecular-weight heparins, glycoprotein IIb/IIIa antagoni...
متن کاملMometasone furoate/formoterol reduces asthma deteriorations and improves lung function.
This study evaluated the effect of mometasone furoate (MF)/formoterol (F) versus its monocomponents, each administered via metered-dose inhaler, on asthma deteriorations and lung function. This 26-week, multicentre, double-blind, placebo-controlled study included subjects aged ≥12 yrs with not well-controlled asthma on low-dose inhaled corticosteroids. After a 2-3-week open-label run-in (MF 100...
متن کامل190 Effect of Mometasone Furoate/Formoterol Combination Therapy on Nocturnal Awakenings in Subjects With Persistent Asthma
AUC0–12h values with MF/F 200/10 mg, MF/F 400/10 mg, and MF 400 mg correspond to average hourly increases of 0.30, 0.35, and 0.17 L, respectively. MF/F was associated with a rapid (,5 minutes) and sustained improvement in lung function. The percentages of subjects experiencing an asthma deterioration (ie, severe asthma exacerbation) were 12.4% (MF/F 200/10 mg), 12.2% (MF/F 400/10 mg), and 18.3%...
متن کاملLong-Term Safety of Mometasone Furoate/Formoterol Combination for Treatment of Patients with Persistent Asthma
OBJECTIVE The combination of inhaled corticosteroid (ICS) and long-acting β₂-agonist is recommended for treatment of patients with persistent asthma inadequately controlled on ICS monotherapy. This study was conducted to evaluate the long-term safety of mometasone furoate/formoterol (MF/F) administered through metered-dose inhaler (MDI) in patients with persistent asthma previously on medium- t...
متن کاملEffect of mometasone furoate/formoterol combination therapy on nocturnal awakenings in subjects with persistent asthma
Methods Subjects were asthmatics previously using low(n=746), medium(n=781) or high-dose (n=728) inhaled corticosteroids ICS. Low-dose subjects were randomized to 26-wk treatment with MF/F 100/10μg, MF 100μg, F 10μg, or placebo; medium-dose subjects to 26-wk treatment with MF/F 200/10μg, MF 200μg, F 10μg, or placebo; high-dose subjects to 12-wk treatment with MF/F 400/10μg, MF/F 200/10μg, or MF...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2019
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2018.10.065